As Rome prepares for its Carnivale, vampire hunter Lady Victoria Gardella is in no mood for festivities. But her personal grief must be set aside for there is a sinister plot underway. In yet another play for power, vampires have formed an unholy alliance with the demon Akvan in order to gain access to an ancient alchemist's secrets. As their combined bloodthirsty army ravages the city streets, Victoria races to solve the age-old mystery - if she fails, the world is lost for ever.